Target New ArrivalsHalloweenClothing, Shoes & AccessoriesHome & DecorKitchen & DiningPatio, Lawn & GardenGroceryHousehold EssentialsBabyBeautyTarget Beauty StudioPersonal CareSports & OutdoorsPetsHealthWellnessSchool & Office SuppliesToys & GamesElectronics & TechVideo GamesBooks, Music & MoviesParty SuppliesGift IdeasGift CardsShop by CommunityTarget OpticalDealsClearanceNew ArrivalsBack to SchoolCollegeTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores
Systane Pro with Hyaluronate Preservative Free Multi-Dose Lubricant Eye Drops - 2 of 4Systane Pro with Hyaluronate Preservative Free Multi-Dose Lubricant Eye Drops - 3 of 4Systane Pro with Hyaluronate Preservative Free Multi-Dose Lubricant Eye Drops - 4 of 4
Systane Pro with Hyaluronate Preservative Free Multi-Dose Lubricant Eye Drops - 1 of 4

Systane Pro with Hyaluronate Preservative Free Multi-Dose Lubricating Dry Eye Drops 12 Hour Relief - 0.34 fl oz

8 Questions
$19.39 ($57.03/fluid ounce)
 
Capacity1pk

In Stock

Eligible for registries and wish lists
Save 5% every day
With Target Circle™ Card (restrictions apply)

At a glance

About this item

Highlights

  • Systane PRO Lubricant Eye Drops feature a triple-action formula that helps hydrate, restore, and protect dry eyes for up to 12 hours
  • The formula includes Hyaluronate, a naturally occurring moisturizer in your eyes. Systane PRO instantly soothes dry eyes
  • Unique formula that covers the surface of the eye for instant hydration and soothing dry eye relief
  • Provides relief from discomfort caused by environmental factors like wind or sun exposure to prevent further dryness and irritation
  • The gentle, preservative-free formula is suitable for use with contact lenses (not a rewetting drop), sensitive eyes and provides multi-symptom dry eye relief
  • The easy-to-use multi-dose bottle is designed for daily, on-the-go hydration
  • Systane is a trusted name in eye care, recommended by eye care professionals for its effective and reliable dry eye relief

Description

Systane® PRO Preservative Free Lubricating Eye Drops feature a triple-action formula that helps hydrate, restore, and protect dry eyes for up to 12 hours of relief. Helps soothe irritation caused by environmental factors like wind and sun. Formulated with the active ingredient Propylene Glycol to lubricate and soothe dry eyes, and HP-Guar and Hyaluronate. The preservative-free formula of Systane Pro Eye Drops also helps lock in moisture and reduce tear evaporation for long lasting comfort. These gentle eye lubricant drops for dry eyes are ideal for sensitive eyes and suitable for use with soft contact lenses (not a rewetting drop). Conveniently packaged in a multi-dose bottle, Systane PRO Preservative Free offers on-the-go hydration that keeps eyes comfortable and moisturized wherever your day takes you. Systane® is a trusted name in eye care, recommended by eye care professionals for reliable relief.
Suggested Age: All Ages
Health Facts: Preservative-Free
Product Warning: Keep out of reach of children
Product Form: Drops
Primary Active Ingredient: Propylene Glycol
Package Quantity: 1
Contact Lens Type: Not Recommended for Contacts
TCIN: 93302712
UPC: 300653290033
Item Number (DPCI): 245-09-9592
Origin: Made in the USA
If the item details aren’t accurate or complete, we want to know about it.

Active ingredients

propylene glycol' '0.6%

Purpose

Lubricant

Uses

Uses for the temporary relief of burning and irritation due to dryness of the eye, for the temporary relief of discomfort due to minor irritations of the eye or to exposure to wind or sun, for use as a protectant against further irritation or to relieve dryness of the eye, for use as a lubricant to prevent further irritation or to relieve dryness of the eye

Directions

Directions shake well before using, put 1 or 2 drops in the affected eye(s) as needed, see side of carton for directions for use

Other information

Other Information store at room temperature

Inactive ingredients

boric acid, dimyristoyl phosphatidylglycerol, hydroxypropyl guar, mineral oil, polyoxyl 40 stearate, sodium hyaluronate, sorbitan tristearate, sorbitol and purified water. may contain hydrochloric acid and/or sodium hydroxide to adjust ph.

Shipping details

Estimated ship dimensions: 4.09 inches length x 1.77 inches width x 1.37 inches height
Estimated ship weight: 0.04 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: How many days will this last? How many applications per bottle?

submitted by FR - 4 months ago

  • A: If you used 2 drops per eye every day, the bottle should last about 2 months from my estimation of 0.05ml/drop. Thanks for your interest in Systane Pro!

    submitted byAlcon Product Expert - 4 months ago
    Brand expert

  • A: Online instructions are to discard Systane Pro PF 30 days after opening. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=23b3515f-fbe5-4398-b2df-8b2eccdd01e2&type=display

    submitted byHope this Helps - 3 months ago

Q: Where in my Bldg did the Shopper leave my pkgs?

submitted by Mary Ay - 1 year ago

  • A: I can only answer questions related to this product and I am not a Target employee. I think you will want to go to your purchase history and click on your order and select Fix an issue to get help with an order. Good luck!

    submitted byAlcon Product Expert - 1 year ago
    Brand expert

Q: How many times a day can use these drops

submitted by Tpmama - 9 days ago

  • A: Systane® PRO Preservative-Free with Hyaluronate can be used as needed throughout the day to relieve dry eye symptoms. Most people use 1-2 drops in the affected eye(s) whenever they experience dryness or irritation. These drops are Preservative-Free and are recommended for people with sensitive eyes or for people that use their drops 4+ times per day. Thanks for your interest in Systane Pro!

    submitted byAlcon Product Expert - 9 days ago
    Brand expert

Q: Can you use these drops after cataract surgery?

submitted by LFF - 1 month ago

  • A: If your eye surgeon recommended an over-the-counter dry eye drop, then yes! Systane® Pro is a lubricating eye drop designed to provide relief from dry eye symptoms. We always recommend to consult your eye surgeon or eye care professional before using any over-the-counter eye drops following cataract surgery. Thanks for your interest in Systane Pro!

    submitted byAlcon Product Expert - 1 month ago
    Brand expert

Q: Can you use these drops with contacts?

submitted by LMeyer - 6 months ago

  • A: Yes, Systane Pro Preservative Free eye drops are safe to use while wearing soft contact lenses. Thanks for your interest in Systane Pro!

    submitted byAlcon Product Expert - 6 months ago
    Brand expert

Q: Where do I find items “saved for later”?

submitted by Rosie - 9 months ago

  • A: Hello, you can find your "save for later" items by clicking on your cart and scrolling down. Thanks!

    submitted byAlcon Product Expert - 9 months ago
    Brand expert

Q: What is difference between Systane Complete and the new formula of Systane Pro? I teach all day and my eyes get so dry and red. Thank you!

submitted by Teacher - 10 months ago

  • A: Systane Pro is our most advanced formula and includes hyaluronate, which can provide up to 12 hours of dry eye relief. It sounds like you are looking for something to get you through the whole day, and this is it! Thank you for your interest in Systane!

    submitted byAlcon Product Expert - 10 months ago
    Brand expert

Q: Are these eye drops safe for an 8 year old?

submitted by Maggy D - 1 year ago

  • A: Yes these are safe for kids, but we recommend consulting with your child’s health care professional before starting the use of dry eye drops. Thanks for your interest in Systane!

    submitted byAlcon Product Expert - 1 year ago
    Brand expert
See all questions (8)

Additional product information and recommendations

Discover more options

Skip to next section

Guests also viewed

Skip to next section
4.7 out of 5 stars with 1055 reviews
94% would recommend
84 recommendations
1 out of 5 stars
1 August, 2026Verified purchase

(no review title)

You left my package in the building next door, my apartment entrance is on the 10 th street, not Vine Street.
Chtis
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
1 August, 2026Verified purchase

Dazzling Drops

After my optometrist showed me these new drops without preservatives, I was sold. I use Restasis for my dry eyes twice a day and these are great for inbrtween
Bonnebelle
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
10 July, 2026Verified purchase

Provide Relief For Dry Eyes

I use these drops at night and they provide relief throughout the whole night.
Did you find this review helpful?
3 out of 5 stars
Thumbs down graphic, would not recommend
27 June, 2026Verified purchase

Eye drops

Shirt nozzle! Why change the style. Now very hard to use
Carol
Did you find this review helpful?
4 out of 5 stars
19 April, 2026Verified purchase

(no review title)

Lubricated my eyes well.
kitty
Did you find this review helpful?
5 out of 5 stars
Thumbs up graphic, would recommend
6 April, 2026Verified purchase

Moisturizing eye drops

After my cataract surgery I returned to using the same eye drops I had used for the last 2 year. However, I noticed that the eye drops were irritating my eyes. I had been given several samples of the Systyane PRO by the doctor's office and decided to try them. By day two I noticed my eyes were no longer irritated. I find the eye drops to be very moisturizing. They do require a minute or two to be absorb but then my relief lasts is for hours.
Nana
quality: 5 out of 5
value: 5 out of 5
3 guests found this review helpful. Did you?
1 out of 5 stars
Thumbs down graphic, would not recommend
21 January, 2026

Don't buy!

These eyedrops suck! They leave a weird film on my eye, takes a while to not see blurry. Wish I could return them but I threw away the box they came in. They also don’t feel like they hydrate my eyes are still dry even after putting on eye drops. I like the systane drops that come in a green bottle.
Cloud18
quality: 1 out of 5
value: 1 out of 5
4 guests found this review helpful. Did you?
1 out of 5 stars
25 September, 2025Verified purchase

Damaged items in delivery

Arrived in crushed box though item ok
J
Did you find this review helpful?
5 out of 5 stars
10 August, 2025
originally posted on Alcon Inc.
Image

Amazing drops

[This review was collected as part of a promotion.] I’ve dry eyes so I always have to use artificial tears. The preservative free vials are always expensive. I actually like the PF bottle because it lasts longer & easy to use. I love that the box has 2 bottles…I shared one with my dad who also has dry eyes. These drops are great & lubricate my eyes throughout the day.
Nfldrod
Did you find this review helpful?
5 out of 5 stars
10 August, 2025
originally posted on https://www.myalcon.com/consumer/
Image

Amazing drops

I've dry eyes so I always have to use artificial tears. The preservative free vials are always expensive. I actually like the PF bottle because it lasts longer & easy to use. I love that the box has 2 bottles…I shared one with my dad who also has dry eyes. These drops are great & lubricate my eyes throughout the day.
Nataly
Did you find this review helpful?
5 out of 5 stars
9 August, 2025
originally posted on Alcon Inc.
Image

Great product!

[This review was collected as part of a promotion.] These worked so well for my dry itchy eyes. I used them first thing in the morning and lastly before bed. Great relief and don’t feel like I need to keep applying for the results I love. Highly recommend!
Zabyab29
Did you find this review helpful?
5 out of 5 stars
9 August, 2025
originally posted on Alcon Inc.
Image

Refreshing to the eyes!

[This review was collected as part of a promotion.] I always have a dry eyes because I am wearing my eyeglasses for more than 12 hours everyday but when I tried the systane pro preservative-free eye drops it helps not only with my dry eyes but with my red eyes too after work. I feel like I am refresh after work and not feeling tired. Its really amazing!
Kmish17
Did you find this review helpful?
5 out of 5 stars
9 August, 2025
originally posted on https://www.myalcon.com/consumer/
Image

Great product!

These worked so well for my dry itchy eyes. I used them first thing in the morning and lastly before bed. Great relief and don't feel like I need to keep applying for the results I love. Highly recommend!
Brittany
2 guests found this review helpful. Did you?
5 out of 5 stars
9 August, 2025
originally posted on https://www.myalcon.com/consumer/
Image

Refreshing to the eyes!

I always have a dry eyes because I am wearing my eyeglasses for more than 12 hours everyday but when I tried the systane pro preservative-free eye drops it helps not only with my dry eyes but with my red eyes too after work. I feel like I am refresh after work and not feeling tired. Its really amazing!
Karen
1 guest found this review helpful. Did you?
5 out of 5 stars
7 August, 2025
originally posted on Alcon Inc.
Image

Systane Pro Preservative-Free Eye Drops

[This review was collected as part of a promotion.] The packaging was appealing and the product was easy to open. The product was a little thick and just getting 1 drop at a time was not easy. However, I only had to use once a day as it was long acting.
Veeee
Did you find this review helpful?
4 out of 5 stars
7 August, 2025
originally posted on Alcon Inc.
Image

Great hydration for tired eyes

[This review was collected as part of a promotion.] I’ve tried so many eye drops over the years with little success. The Systane Pro Preservative-Free Eye Drops by far have been the best at rejuvenating my eyes after hours of staring at monitors day in and day out! I certainly would recommend these drops to anyone dealing with dry or tired eyes!
Reeree
Did you find this review helpful?
5 out of 5 stars
7 August, 2025
originally posted on https://www.myalcon.com/consumer/
Image

Systane Pro Preservative-Free Eye Drops

The packaging was appealing and the product was easy to open. The product was a little thick and just getting 1 drop at a time was not easy. However, I only had to use once a day as it was long acting.
VELDA
Did you find this review helpful?
4 out of 5 stars
7 August, 2025
originally posted on https://www.myalcon.com/consumer/
Image

Great hydration for tired eyes

I've tried so many eye drops over the years with little success. The Systane Pro Preservative-Free Eye Drops by far have been the best at rejuvenating my eyes after hours of staring at monitors day in and day out! I certainly would recommend these drops to anyone dealing with dry or tired eyes!
Cheri
Did you find this review helpful?
5 out of 5 stars
5 August, 2025
originally posted on Alcon Inc.
Image

View Through Lubricated Lenses

[This review was collected as part of a promotion.] These eye drops are excellent for any irritations or dryness. It is fast-acting, I felt immediate hydration and relief after use.
QueenCassie
Did you find this review helpful?
5 out of 5 stars
5 August, 2025
originally posted on https://www.myalcon.com/consumer/
Image

View Through Lubricated Lenses

These eye drops are excellent for any irritations or dryness. It is fast-acting, I felt immediate hydration and relief after use.
Cassandra
Did you find this review helpful?

Get top deals, latest trends, and more.

Privacy policy
Terms