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Similac Neosure Powder Infant Formula - 22.8oz - 2 of 4Similac Neosure Powder Infant Formula - 22.8oz - 3 of 4Similac Neosure Powder Infant Formula - 22.8oz - 4 of 4
Similac Neosure Powder Infant Formula - 22.8oz - 1 of 4

Similac Neosure Powder Infant Formula - 22.8oz

2 Questions
$48.99 ($2.15/ounce)

In Stock

Eligible for registries and wish lists

At a glance

About this item

Highlights

  • NEOSURE IS THE #1 SELLING PRETERM POST-DISCHARGE INFANT FORMULA
  • FROM THE MAKER OF THE #1 BRAND FED IN THE NICU
  • EXCELLENT CATCH-UP GROWTH: Supports better gains in weight, length, and head circumference for premature babies when compared to term infant formula
  • HELPS SUPPORT BRAIN & EYES: Has DHA and lutein, important components found in breast milk
  • ALSO AVAILABLE IN CONVENIENT READY TO FEED: Great for on-the-go and late-night feeding; no mixing required
  • HELPS SUPPORT BONE GROWTH: Our formula has calcium and phosphorus for baby’s growing bones

Description

Similac NeoSure* premature post-discharge baby formula promotes excellent catch-up growth1 during a premature baby’s first 12 months of life. It has enriched nutrition increased protein, vitamins, and minerals for growth compared to term infant formula—as well as calcium and phosphorus for baby’s growing bones. It has DHA and lutein to help support baby’s brain and eye development, and it has no artificial growth hormones.†
* Not for infants or children with galactosemia.
† Milk ingredients are derived from milk of non-rbST-treated cows, which is not different from milk of rbST-treated cows.
Reference: 1. Carver JD, et al. Pediatrics. 2001;107(4):683-689.

Serving Size: 4.5 fl oz

Amount

% Daily Value*
Total Fat 5.5g
Sodium 33mg
Total Carbohydrate 10.1g
Protein 2.8g
Vitamin D 70IU
Calcium 105mg
Potassium 142mg
Vitamin A 350IU
Vitamin C 15mg
Vitamin E 3.6IU
Vitamin K 11mcg
Thiamin 175mg
Niacin 1950mcg
Vitamin B6 100mcg
Folic Acid 25mcg
Vitamin B12 0.4mcg
Biotin 9mcg
Pantothenic Acid 800mg
Choline 16mg
Phosphorus 62mg
Iodine 15mcg
Magnesium 9mg
Zinc 1.2mg
Selenium 2.3mcg
Copper 120mg
Chloride 75mg
Omega-6 (linoleic acid LA) 750mg
Inositol 35mg
Water 120g
Riboflavin 150mg
* Percentage of Daily Values are based on a 2,000 calorie diet.

Ingredients:

nonfat milk, corn syrup solids, lactose, soy oil, high oleic safflower oil, whey protein concentrate, coconut oil, medium chain triglycerides, less than 2% of: c. cohnii oil, m. alpina oil, beta-carotene, lutein, potassium citrate, calcium phosphate, inositol, ascorbic acid, magnesium chloride, soy lecithin, calcium carbonate, taurine, ferrous sulfate, choline bitartrate, choline chloride, ascorbyl palmitate, l-carnitine, potassium chloride, salt, zinc sulfate, mixed tocopherols, d-alpha-tocopheryl acetate, sodium citrate, niacinamide, potassium phosphate, calcium pantothenate, copper sulfate, vitamin a palmitate, thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, folic acid, manganese sulfate, phylloquinone, biotin, sodium selenate, vitamin d₃, vitamin b₁₂, potassium hydroxide, and nucleotides (adenosine 5'-monophosphate, cytidine 5'-monophosphate, disodium guanosine 5'-monophosphate, disodium uridine 5'-monophosphate)
Dietary Needs: Gluten-Free, Kosher, Halal
Baby Formula Focus: Low Birth Weight, Growth Support, Eye Development, Prematurity, Brain Development
Base Ingredient: Milk
State of Readiness: Mix
Form: Powdered
Package Quantity: 1
Age Stage: Infant
TCIN: 79314589
UPC: 070074669243
Item Number (DPCI): 007-09-8379
Origin: Made in the USA or Imported
Grocery Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers. Any additional pictures are suggested servings only.
If the item details aren’t accurate or complete, we want to know about it.

Shipping details

Estimated ship dimensions: 5.2 inches length x 5.2 inches width x 5.3 inches height
Estimated ship weight: 1.66 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest. If purchased online with SNAP EBT, this item must be returned within 90 days of the date it was shipped, delivered by a Shipt shopper, or made ready for pickup. This 90-day return window is required by SNAP.
See the return policy for complete information.

Q: What's the biggest difference between neosure and 360 total ? Is it safe to have this formula after the first month as I stored up a bit more.

submitted by David - 2 years ago

  • A: Neosure is for premature babies & 360 total is for term babies (37+ weeks). There is a different nutritional make-up. Meaning the 360 total would be deficient for a preterm baby, and possibly give a term baby too much or too little of particular nutrients. You can always verify with your pediatrician

    submitted byNola - 7 months ago

  • A: To best answer your question, please give us a call at 800-232-7677, M-F from 9am-6pm, ET & reference customer# 04772024. Thanks and we hope to hear from you soon. -The Similac Team

    submitted byAbbott Nutrition Team - 2 years ago
    Brand expert

Q: How many fluid ounces of formula does this canister make?

submitted by annon - 29 days ago

  • A: Thanks for your question! To best assist, please give us a call at 800-850-7677, M-F from 8:30AM-5:00PM ET and be sure to reference customer# 05043212. We hope to hear from you soon! - The Similac Team

    submitted byAbbott Nutrition Team - 28 days ago
    Brand expert
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Guests are saying

This formula is highly regarded by guests for its effectiveness in helping premature babies gain weight and thrive. Many guests appreciate its nutritional value and ease of use, especially the ready-to-drink option. However, some guests have noted issues with gas and constipation in their little ones. Overall, it is a recommended choice for parents looking to support their baby's growth, particularly for those born prematurely.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.3 out of 5 stars with 655 reviews
    easy on tummy: 3.58 out of 5
    easy to prepare: 4.62 out of 5
    quality: 4.21 out of 5
    value: 3.65 out of 5
    75% would recommend
    33 recommendations
    5 out of 5 stars
    Thumbs up graphic, would recommend
    22 August, 2026Verified purchase

    NICU Mom Approved

    Baby was in the NICU for 7 weeks! The neonatal docs said this would be the prescribed discharge formula. He’s been doing great on it so far! We actually add in enfamil’s multivitamin with polyvisol as prescribed by his pediatrician, and it does not change the taste for him. Although I’m sure the formula is nutritious enough on its own! It is expensive, but worth it post discharge as he is exclusively formula fed. Hoping it becomes more affordable in the future or one of the larger grocery stores makes a dupe, as it can be hard to find too.
    busybee
    easy on tummy: 4 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 2 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    9 August, 2026Verified purchase

    (no review title)

    My newborn love this since he was in NICU, still using today. And also the ready to drink.
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 4 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    10 July, 2026
    originally posted on similac.com
    Image

    The best choice!

    [This review was collected as part of a promotion.] Discovering these 32oz bottles have been a lifesaver! Preparing bottles for day care has never been easier.
    And0124
    Did you find this review helpful?
    5 out of 5 stars
    8 July, 2026
    originally posted on similac.com
    Image

    Helpful for our baby

    [This review was collected as part of a promotion.] Have been using this formula for our little one and it’s helping him finally gain the weight he needs!
    Justi427
    Did you find this review helpful?
    1 out of 5 stars
    21 April, 2026Verified purchase

    (no review title)

    Multiple times the quantity left has been inaccurate and it’s been inconvenient going to a farther location to pick up the item.
    1 reply from Abbott Nutrition Team team - 5 months ago
    We're sorry to hear this happened! We would suggest contacting the Target.com team directly at 800-591-3869 or clicking the 'Target.com Order Experience' topic under the 'Contact Us' section of the website. -The Similac Team
    Carlos
    2 guests found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    25 March, 2026Verified purchase

    Worked great

    Preemie baby…gained weight, no gas issues. Highly recommend
    Angel
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    25 January, 2026Verified purchase

    (no review title)

    This formula was recommended to be use by our pediatrician as my daughter was born 6 weeks early. She did has issue around 5 week mark with gas but was told that’s normal by our pediatrician. Now almost 4 month she has again an appropriate amount of weight based on her age with this formula. No more gas issue either!!
    1 reply from Abbott Nutrition Team team - 8 months ago
    We would like to learn more about your baby's experience with Similac NeoSure and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04939643 when you call. -The Similac Team
    shocknelle
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    14 January, 2026
    originally posted on similac.com
    Image

    Great Formula

    Best bang for your buck by buying the larger can. Love this formula and all the benefits it has for my baby.
    formula review
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    3 November, 2025
    originally posted on similac.com
    Image

    Wonderful formula

    My granddaughter was 6 weeks premature. Her pediatrician put her on this formula and she has done so well. She has gained weight on a great schedule and is healthy and happy!
    Similac neosure
    1 guest found this review helpful. Did you?
    5 out of 5 stars
    17 October, 2025Verified purchase

    (no review title)

    Excellent I love these
    Betty
    Did you find this review helpful?
    5 out of 5 stars
    29 September, 2025
    originally posted on similac.com
    Image

    Great!

    So easy to use just pour and heat the bottle after opening
    Bbrown
    Did you find this review helpful?
    5 out of 5 stars
    20 September, 2025
    originally posted on similac.com
    Image

    N/a

    My baby’s milk and is been amazing for him. Since birth
    JR24
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    29 August, 2025Verified purchase

    Wonderful Product

    Mixes well in water, no tummy trouble from formula, great nutritional value
    Crystal
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?
    3 out of 5 stars
    Thumbs down graphic, would not recommend
    20 August, 2025Verified purchase

    Reflux issues

    Recommended by hospital pediatrician for my premature twins so that they can gain weight. At first, they did okay and did gain weight but then they started to have really bad reflux after every feeding. Switched to an organic formula due to this.
    1 reply from Abbott Nutrition Team team - 1 year ago
    We know finding the right formula can be a challenge, but our team is here to help. Feel free to give us a call so we can learn more: 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04871608. Thanks, and we hope to hear from you soon! -The Similac Team
    Angel
    easy on tummy: 1 out of 5
    easy to prepare: 5 out of 5
    quality: 2 out of 5
    value: 2 out of 5
    4 guests found this review helpful. Did you?
    5 out of 5 stars
    8 July, 2025
    originally posted on similac.com
    Image

    Great product

    I recently bought this and so glad I did. My baby loves it
    Aimh
    Did you find this review helpful?
    5 out of 5 stars
    Thumbs up graphic, would recommend
    6 July, 2025Verified purchase

    Best Formula For Preemies

    My son was a preemie and he loved this formula. It really bulked him up quick and now he's above the 50 percentile. It is really expensive though, but that's the only downside to it.
    Jhigs
    easy on tummy: 5 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 4 out of 5
    1 guest found this review helpful. Did you?
    3 out of 5 stars
    Thumbs down graphic, would not recommend
    19 June, 2025Verified purchase

    Don't buy

    This tore my twin babies bellies up! It was so harsh. Good source of calories and nutrients but not worth the pain they had.
    1 reply from Abbott Nutrition Team team - 1 year ago
    We would like to learn more about your twin's experiences with NeoSure and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04841464 when you call. -The Similac Team
    Do not buy
    easy on tummy: 1 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 2 out of 5
    3 guests found this review helpful. Did you?
    1 out of 5 stars
    Thumbs down graphic, would not recommend
    16 February, 2025

    Really hard on the tummy

    Helps baby gain weight, but made her so gassy and uncomfortable.
    1 reply from Abbott Nutrition Team team - 2 years ago
    We know finding the right formula can be a challenge, but our team is here to help. Feel free to give us a call so we can learn more: 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer #04790271. Thanks, and we hope to hear from you soon!
    Alysha
    easy on tummy: 1 out of 5
    easy to prepare: 5 out of 5
    quality: 5 out of 5
    value: 3 out of 5
    3 guests found this review helpful. Did you?
    5 out of 5 stars
    8 February, 2025
    originally posted on similac.com
    Image

    Great item

    My child loves it she is not gassey or spitting up since i switched her to the powder
    Msmeah
    Did you find this review helpful?
    4 out of 5 stars
    5 February, 2025
    originally posted on similac.com
    Image

    Satisfied

    The NICU started my baby on this formula. I wanted to switch to a cheaper competitor, but two pediatricians advised to stick with Similac Neosure because my baby was doing so well on it and doubled his weight! He does seem to have a lot of gas, but I will live with it since we are relieved to hear that has grown so much and went from the 27 percentile to 49 percentile for his age group.
    1 reply from The Consumer Relations Team team - 2 years ago
    Thanks for your review! We would like to learn more about your baby's experience with Similac NeoSure and hope you can give us a call when you have a few minutes to spare. Our team can be reached at 800-850-7677, M-F from 8:30am-5pm, ET & be sure to reference customer# 04777195 when you call.
    Anonymous1
    1 guest found this review helpful. Did you?

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