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Depend Night Defense Incontinence Disposable Underwear for Men - Overnight Absorbency - 2 of 4Depend Night Defense Incontinence Disposable Underwear for Men - Overnight Absorbency - 3 of 4Depend Night Defense Incontinence Disposable Underwear for Men - Overnight Absorbency - 4 of 4
Depend Night Defense Incontinence Disposable Underwear for Men - Overnight Absorbency - 1 of 4

Depend Night Defense Incontinence Disposable Underwear for Men - Overnight Absorbency - L - 14ct

14 Questions
$15.89 ($1.14/count)
 
SizeL
Count14ct

In Stock

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At a glance

About this item

Highlights

  • WHAT'S INCLUDED — 14 count of Depend Night Defense Adult Incontinence Underwear for Men, maximum absorbency, size large (35–43" waist)
  • OUTSTANDING ABSORBENCY — Depend DryShield core absorbs 30x its weight* to help keep you dry and turns liquid into gel (*super absorbent material absorbs 30x its weight)
  • UP TO 12 HOURS OF PROTECTION — Designed for up to 12 hours of overnight protection and worry-free sleep
  • UNDERWEAR-LIKE COMFORT — Our disposable incontinence underwear designed for men feels like real underwear for superior comfort** and confidence, even overnight (**vs. previous Depend Night Defense)
  • UP TO ZERO ODOR — Depend underwear has up to zero odors thanks to ODORBLOCK technology that helps neutralize and lock in odors
  • UNCOMPROMISED COMFORT — These bladder leak underwear are designed with ultra-soft material, unlike some adult diapers, making them more comfortable than ever before
  • COTTON-LIKE FABRIC — Depend’s bladder leak underwear is made with cotton-like fabric and is softer and quieter than before for extra comfort and peace of mind
  • HSA/FSA ELIGIBLE — Depend incontinence products are HSA/FSA-eligible in the US (check with your provider for coverage details)

Description

Depend Night Defense Underwear for Men delivers up to 12 hours of protection and underwear-like comfort. Offering up to zero odor, our adult diapers for men are made with ODORBLOCK technology that helps neutralize and lock in odors. Depend Night Defense helps protect you from overnight bladder leaks thanks to our Dryshield core that absorbs 30x its weight* and turns liquid into gel. More comfortable than ever, our incontinence underwear for men is made with cotton-like fabric and materials that are softer and quieter than before. A moisture-wicking layer for dryness provides gentle protection you can trust through the night. Depend Night Defense incontinence underwear for men is available in three sizes: size small/medium (26–34" waist), size large (35–43" waist) and size extra-large (44–54" waist). Depend incontinence underwear is HSA/FSA-eligible in the US — check with your provider for coverage details. For daytime protection, try Depend Fresh Protection Underwear. Packaging may vary. (*super absorbent material absorbs 30x its weight)
Health Facts: No Fragrance Added
Disposability: Do not flush
Absorbency: Overnight
Package Quantity: 14
Number of units per package: 14
Minimum Waist Size: 35 Inches
Maximum Waist Size: 43 Inches
Features: Disposable, Nighttime Use, Leak Protection
TCIN: 79330408
UPC: 036000511253
Item Number (DPCI): 245-01-8546
Origin: Made in the USA or Imported
If the item details aren’t accurate or complete, we want to know about it.

Ingredients:

sodium polyacrylate, cellulose, polypropylene, hydrocarbon resin, polyester, polyethylene, spandex, styrene/isoprene copolymer, titanium dioxide, peg-10, oleyl palmitamide, pigment blue 29, pigment black 7, sorbitan laurate, sorbitan oleate, pigment blue 15, pigment red 122, diethylhexyl sodium sulfosuccinate, sodium laureth-4 phosphate, zinc oxide, pigment red 254, solvent blue 104, pigment red 57:1.

Shipping details

Estimated ship dimensions: 5.77 inches length x 9.23 inches width x 9.67 inches height
Estimated ship weight: 1.93 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 90 days of the date it was purchased in store, delivered to the guest, delivered by a Shipt shopper, or picked up by the guest.
See the return policy for complete information.

Q: If my waist size is 34 should I get a medium or large

submitted by me - 5 months ago

  • A: Thanks for your question. We'd recommend starting with a S/M size.

    submitted byDependExpert - 5 months ago
    Brand expert

  • A: Daz daw aws was 2w wwd a Awash q aW wawa q

    submitted byWawa zant - 3 months ago

Q: Can these be worn all day

submitted by Nana - 4 years ago

  • A: yes it can . it obsorbs a lot of urine.

    submitted bydiaper boy - 3 years ago

  • A: Hi Nana, our Night Defense Underwear provides protection from bladder leaks for up to 12 hours. We hope this helps!

    submitted byDependExpert - 4 years ago
    Brand expert

Q: How many ML will these hold

submitted by Rusty - 2 months ago

  • A: Hi Rusty. Our Night Defense Underwear for Men can hold up to 30 ounces (or up to 887 ml). Hope this helps.

    submitted byDependExpert - 2 months ago
    Brand expert

Q: Is there a marking to indicate front or back of the nighttime underwear?

submitted by Tom - 7 months ago

  • A: Hi Tom! Each of our underwear products have a visible indicator on the inside of the product to show which side should be in the front or back.

    submitted byDependExpert - 7 months ago
    Brand expert

Q: Will this product help with absorbtion of urine if sleeping on back?

submitted by Grandma G - 1 year ago

  • A: Thanks for your question. Yes, Night Defense® Underwear for Men are designed for more leakage coverage while lying down. It also offers nighttime protection from urinary leaks for up to 12 hours and features form-fitting leg elastics for a discreet fit under pajamas.

    submitted byDependExpert - 1 year ago
    Brand expert

Q: Has the absorpency formula for the Night Defense Depense been changed recently? My husband has had, within the past 2 months, multiple leaking issues with this product.

submitted by Caretaker Wife - 1 year ago

  • A: We're sorry to hear about your husband's recent experience with our Depend Night Defense Underwear. We'd like the opportunity to learn more to see how we can help. Please give us a call at 1-877-413-3736 (Monday–Friday from 8am-5pm CST). We hope to hear from you soon.

    submitted byDependExpert - 1 year ago
    Brand expert

Q: Will the diaper contain bowel incontinence

submitted by Tony - 2 years ago

  • A: Hi Tony. Our Depend® products are designed and tested for urinary incontinence, not bowel incontinence. Thank you for reaching out, and we hope this helps!

    submitted byDependExpert - 2 years ago
    Brand expert

Q: What is the proper way to put on night defense depends

submitted by Max - 2 years ago

  • A: Hi Max! Depend Night Defense is designed to look and feel like underwear. They do not have tape fasteners, so you can easily slip them on.

    submitted byDependExpert - 2 years ago
    Brand expert

Q: i want to order 7 of these diapers plus CaDCADE DISHWASHING DETERGENT

submitted by MARGARET - 4 years ago

  • A: Hi MARGARET, please reach out to Target directly for the best assistance at 1 (800) 440-0680. Thank you.

    submitted byDependExpert - 4 years ago
    Brand expert

Q: what size depends for 38" waist

submitted by OZ - 5 years ago

  • A: Thank you for your question. Our Depend Night Defense in size large is for pant sizes 35-43. We hope this helps!

    submitted byDependExpert - 5 years ago
    Brand expert
See all questions (14)

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4.6 out of 5 stars with 1525 reviews
comfort: 4.44 out of 5
effectiveness: 4.22 out of 5
quality: 4.34 out of 5
value: 4.17 out of 5
79% would recommend
67 recommendations
5 out of 5 stars
1 September, 2026
originally posted on depend.com
Image

Nice snug close fit and most importantly dry!

[This review was collected as part of a promotion.] These have really been a great change up from our recent nighttime diapers. So far no worries about moving around and leaking out. They are snug and comfy.
JesseS
Did you find this review helpful?
5 out of 5 stars
27 August, 2026
originally posted on depend.com
Image

They are very comfortable.

[This review was collected as part of a promotion.] The men’s Depends night defense bladder leak underwear in size extra large are great. They fit perfect size and don’t punch up and don’t leave marks in my stomach when wearing. They are very comfortable and honestly, you can’t even tell they’re there after wearing them for a while. I have had no issues with leaking, which is a huge thing and definitely something that I look for and want. I love that they don’t leave unwanted smells either. I’m very pleased with them.
MichaelB
Did you find this review helpful?
3 out of 5 stars
27 August, 2026
originally posted on depend.com
Image

Comfy

[This review was collected as part of a promotion.] These are very reliable and comfy even after filling the diaper up you’ll feel dry and it doesn’t leak even with a heavy load due to its high absorbing material
JoseO
Did you find this review helpful?
5 out of 5 stars
23 August, 2026
originally posted on depend.com
Image

skin

[This review was collected as part of a promotion.] I’m very impressed with Depend Men Night Defense underwear. The material feels soft and comfortable, while the underwear-like design makes it discreet and easy to wear. It provides excellent overnight protection and gives me peace of mind while sleeping. I also like the odor control, which helps me feel fresh and confident. The fit is secure without feeling too tight or bulky, and it stays in place well throughout the night. Overall, this is a reliable product for anyone who needs extra protection from bladder leaks. I would definitely recommend it and would purchase it again.
KentH
Did you find this review helpful?
5 out of 5 stars
22 August, 2026
originally posted on depend.com
Image

Great adult bladder leak underwear

[This review was collected as part of a promotion.] The Depend Night Defense Bladder Leak Underwear was very comfortable, they felt very durable not bulky and they were extremely breathable! I felt very secure knowing that if there were to be an accident nothing would leak through.
BryceJ
Did you find this review helpful?
5 out of 5 stars
22 August, 2026
originally posted on depend.com
Image

Good fit, breathable, and they do the job

[This review was collected as part of a promotion.] I tried these and urinated in them intentionally before taking a shower. They fit very comfortably and did not leak at all. I wasn’t sure if I could use them after washing so I disposed of the soiled pair, but they were truly effective and soaked up the moisture while remaining very dry. I have a little incontinence while sleeping and sometimes on long airplane flights. I will be using them in the future. I didn’t take a picture wearing the underwear because I thought that might be inappropriate. I would definitely recommend if you have a compromised bladder and can’t hold it.
EricC
Did you find this review helpful?
5 out of 5 stars
21 August, 2026
originally posted on depend.com
Image

Comfortable, discreet and reliable overnight protection!

[This review was collected as part of a promotion.] The Depends Night Defense underwear for men provided me with a comfortable fit throughout the night without feeling overly thick or cumbersome, which was especially important to me when evaluating a protective product. They remained securely in place while I slept and offered reliable protection against bladder leaks, allowing him to wake up feeling dry and comfortable. The fabric feels soft and breathable, while the overall design is discreet and resembles regular underwear rather than traditional protective garments. I was also impressed with the odor-control feature, which added another level of comfort and confidence during overnight use.
HungB
Did you find this review helpful?
5 out of 5 stars
19 August, 2026
originally posted on depend.com
Image

Great experience with them!

[This review was collected as part of a promotion.] I got these for my dad, and they have been really helpful for him. They’re comfortable, provide great coverage, and give him extra protection and peace of mind, especially throughout the night. Overall, great experience with them.
RobertC
Did you find this review helpful?
5 out of 5 stars
19 August, 2026
originally posted on depend.com
Image

Unexpected surprise

[This review was collected as part of a promotion.] I was a bit skeptical at first but I have to say these were very comfortable and I even wore them thru the night and almost forgot I had them on. I can see as an emergency if you really need to use them or close to a last cade resort they will exactly what's intended and get the job doen right
JoseE
Did you find this review helpful?
5 out of 5 stars
18 August, 2026
originally posted on depend.com
Image

Be discreet

[This review was collected as part of a promotion.] They feel comfortable keeps me dry, amazing absorption, very discreet, and no noise. I would recommend to a friend not too much exposure nothing revealed
perryC
Did you find this review helpful?
5 out of 5 stars
18 August, 2026
originally posted on influenster.com
Image

skin

I’m very happy with these Depend Men Night Defense underwear. They are soft, comfortable, and provide excellent protection throughout the night. The fit feels secure without being too tight, and the underwear-like design makes them more discreet and comfortable than traditional adult briefs. I especially like the odor control and the up-to-12-hour protection, which gives me extra peace of mind while sleeping. The material is also noticeably softer and quieter than some other brands I’ve tried. They are easy to put on and stay in place well during the night. Overall, these are a great choice for anyone looking for reliable overnight protection, comfort, and discretion. I would definitely purchase them again.
KentH
Did you find this review helpful?
5 out of 5 stars
16 August, 2026
originally posted on depend.com
Image

Amazing Incontinence Underwear for men

[This review was collected as part of a promotion.] Depend Night Defence Underwear fir men comes with DryShiekd cire which abdorbs 30 times its weight to help keep me dry which turns liquid into gel which is absolutely amazing technology for sure.
AsimM
Did you find this review helpful?
5 out of 5 stars
14 August, 2026
originally posted on depend.com
Image

If you need bladder control protection, this product is good for you. I appreciate the way it's made.

[This review was collected as part of a promotion.] The scent of the product was fine. The fit was comfortable and it’s very covering. It was very convenient. The material feels very good and the fit is very nice. I would recommend this product.
RobertW
Did you find this review helpful?
5 out of 5 stars
13 August, 2026
originally posted on depend.com
Image

Diapers

[This review was collected as part of a promotion.] These fit my grandpa very nicely he struggles a lot to make it to the bathroom and these are a lifesaver. He says they are very comfortable and he liked them more then the other options
JorgeE
Did you find this review helpful?
3 out of 5 stars
11 August, 2026
originally posted on depend.com
Image

Confort at it's best

[This review was collected as part of a promotion.] The Depends Blatter Leak is a nice product to have. It makes your confidence go up having something to protect you while sleeping and day to day. The price doesn't break the bank and the confort is excellent.
AlvinD
Did you find this review helpful?
5 out of 5 stars
11 August, 2026
originally posted on depend.com
Image

Great underwear!

[This review was collected as part of a promotion.] I used these overnight and was impressed by how comfortable and secure they felt. The material is soft and breathable, helping prevent irritation while sleeping. Despite the extra absorbency, they fit discreetly under clothing and didn't feel bulky. They provided reliable protection throughout the night, keeping me dry and confident until morning. The stretchy waistband offers a comfortable fit, and the packaging makes it easy to store and grab when needed. Overall, it's a dependable option for overnight protection and peace of mind.
VictorA
Did you find this review helpful?
5 out of 5 stars
11 August, 2026

(no review title)

Works Good.
Did you find this review helpful?
5 out of 5 stars
9 August, 2026
originally posted on influenster.com
Image

Holds up great!

These are great for my grandpa who wouldn’t be able to get up in time to make it to the bathroom. He now wears these at night. He loves how comfortable they are. Nothing seeps through either which is something he worried about.
MckadeE
Did you find this review helpful?
5 out of 5 stars
3 August, 2026
originally posted on depend.com
Image

Comfortable and reliable night protection for leak control

[This review was collected as part of a promotion.] Depend Night Defense offers a good combination of protection, comfort and discretion. Its underwear design allows for a safe and comfortable fit at night, while absorption helps control bladder leakage and keep skin drier. The material is lightweight, soft and does not limit movement, ideal for resting with greater confidence. S/M size fits well for small to medium bodies and provides good stamina without feeling too bulging. It is a functional option for those looking for night protection that looks similar to traditional underwear.
DO64459DanielG
Did you find this review helpful?
5 out of 5 stars
30 July, 2026
originally posted on depend.com
Image

Super stretchy amazing absorbers!

[This review was collected as part of a promotion.] I thought these would be super tiny since I’m 6’1 and 200lbs, but they’re so stretchy! And they hold so much liquid! A whole water bottle! They didn’t spill a drop! These definitely do the trick
SteveW
1 guest found this review helpful. Did you?

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